Polypill

Power of one: what is holding polypills back?Subscription

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Single pills with fixed-dose combinations of several medicines are not commonplace for the treatment of cardiovascular disease. As the first randomised controlled trial to show a polypill can cut the risk of heart attacks is published, we look at why, nearly two decades after it was first proposed, development and uptake is limited. 

Oral Insulin

Binning the sharps: the quest for oral insulinSubscription

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The pharmaceutical industry has been trying to develop oral formulations of insulin since the 1920s without success, but, over the past few years, several new oral delivery systems have shown promise in clinical trials.

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